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High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells

2022-07-24

Abstract excerpt

<h4>ABSTRACT</h4> Long-term immunity to SARS-CoV-2 infection, including neutralizing antibodies and T cell-mediated immunity, is required in a very large majority of the population in order to reduce ongoing disease burden. We have investigated the association between memory CD4 and CD8 T cells and levels of neutralizing antibodies in convalescent COVID-19 subjects. Higher titres of convalescent neutralizing antib...

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Literature Corpus work
a79f5082-39e4-50e1-9057-99f9a411467e
DOI
10.1101/2022.07.22.22277947
Open publication

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High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cellsDOI 10.1101/2022.07.22.22277947
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