Article
Nanoscale Particles for Lung Delivery of siRNA
2012-01-01
Abstract excerpt
Small interfering RNAs (siRNAs) are potent molecules capable of blocking gene expression after entering cell cytoplasm. Despite their strong efficacy, they need to be carried by nanoscale delivery systems that can protect them against degradation in biological fluids, increase their cellular uptake and favor their subcellular distribution. Several studies have highlighted the potential of local pulmonary delivery...
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Identifiers and source
- Literature Corpus work
- 8a7a2fff-7b67-5994-baeb-b2779276ba66
- DOI
- 10.1016/s1773-2247(12)50010-9
- PMCID
- PMC7128800