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Nanoparticulate RNA delivery systems in cancer

30 Jul 2020

Abstract excerpt

BACKGROUND: Drug delivery system is a common practice in cancer treatment. RNA interference-mediated post-transcriptional gene silencing holds promise as an approach to knockdown in the expression of target genes responsible for cancer cell growth and metastasis. RNA interference (RNAi) can be achieved by delivering small interfering RNA (siRNA) and short hairpin RNA (shRNA) to target cells. Since neither...

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PMID: 32729987
DOI: 10.1002/cnr2.1271

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