Advancements in gene therapy for lung cancer: from genetic insights to clinical applications

Abstract excerpt

Gene therapy represents a transformative approach in lung cancer treatment, leveraging strategies such as gene replacement, editing and silencing to target oncogenes and restore tumor suppressor functions. Techniques like CRISPR/Cas9, RNA interference and viral vectors, including adenoviruses and Adeno-Associated Virus (AAVs), have shown promise in overcoming drug resistance and enhancing immune responses....

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