Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.

Epilepsia - 1 Jul 2012

Cao Dezhi, Ohtani Hideyuki, Ogiwara Ikuo, Ohtani Sanae, Takahashi Yukitoshi, Yamakawa Kazuhiro, Inoue Yushi

Abstract excerpt

PURPOSE: We previously reported a mutant mouse carrying a severe myoclonic epilepsy in infancy (SMEI) mutation in Scn1a. In this study, we examined the susceptibility to hyperthermia-induced seizures of heterozygous Scn1a mutant mice (Scn1a(RX/+)) and wild-type (Scn1a(+/+) ) mice. Then we assesse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Benzodiazepines
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electroencephalography

Share to Epilepsies, Myoclonic

Share to NAV1.1 Voltage-Gated Sodium Channel

Share to Seizures

Share to Sodium Channels

Source

Identifiers

PMID: 22578034
DOI: 10.1111/j.1528-1167.2012.03497.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22578034-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.PMID 22578034Read ↗

Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS contract site for the Epilepsy Therapy Screening ProgramSemantic proximity Read ↗

A novel rat model of Dravet syndrome recapitulates clinical hallmarksSemantic proximity Read ↗

Sexual dimorphism in epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the <i>Scn1a</i> geneSemantic proximity Read ↗

Life-span characterization of epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the Scn1a geneSemantic proximity Read ↗

Therapy for hyperthermia-induced seizures in Scn1a mutant rats.Semantic proximity Read ↗

Heat-induced seizures, premature mortality, and hyperactivity in a novel <i>Scn1a</i> nonsense model for Dravet syndromeSemantic proximity Read ↗

A 5-HT1D -receptor agonist protects Dravet syndrome mice from seizure and early death.Semantic proximity Read ↗

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndromeSemantic proximity Read ↗

Proteomic signature of the Dravet syndrome in the genetic <i>Scn1a</i> -A1783V mouse modelSemantic proximity Read ↗

Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutationSemantic proximity Read ↗

Evaluation of clinically relevant sevoflurane concentrations in the development of malignant hyperthermia in an Ryr1 mutant mouse model.Semantic proximity Read ↗

[Clinical features and SCN1A gene mutation analysis of severe myoclonic epilepsy of infancy].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.