Article

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants

2022-01-13

Abstract excerpt

<h4>Summary</h4> The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered a devastating global health, social and economic crisis. The RNA nature and broad circulation of this virus facilitate the accumulation of mutations, leading to the continuous emergence of variants of concern with increased transmissibility or pathogenicit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 89bd7db0-d939-5bdc-8e35-bcf167294a84
DOI: 10.1101/2022.01.12.22269023

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variantsDOI 10.1101/2022.01.12.22269023Read

Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variantsSemantic proximity Read

A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralizationSemantic proximity Read

An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by several therapeutic monoclonal antibodiesSemantic proximity Read

An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoV-2 variantsSemantic proximity Read

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH DomainsSemantic proximity Read

Potent neutralization by a receptor binding domain monoclonal antibody with broad specificity for SARS-CoV-2 JN.1 and other variantsSemantic proximity Read

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodiesSemantic proximity Read

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.Semantic proximity Read

Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster modelsSemantic proximity Read

Development of Potent and Effective Synthetic SARS-CoV-2 Neutralizing NanobodiesSemantic proximity Read

Preclinial Safety and Efficacy of a Therapeutic Antibody That Targets SARS-CoV-2 at the Sotrovimab Face But is Escaped by OmicronSemantic proximity Read

Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational lockingSemantic proximity Read