Article

A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization

2022-07-29

Abstract excerpt

<h4>Summary Paragraph</h4> Despite effective countermeasures, SARS-CoV-2 persists worldwide due to its ability to diversify and evade human immunity 1 . This evasion stems from amino-acid substitutions, particularly in the receptor-binding domain of the spike, that confer resistance to vaccines and antibodies 2–16 . To constrain viral escape through resistance mutations, we combined antibody variable regions th...

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Literature Corpus work: 4efb78c4-020b-5715-bc76-0fd78b24db75
DOI: 10.1101/2022.07.29.502029

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