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Blood Gene Expression and Immune Cell Subtypes Associated with Chronic Obstructive Pulmonary Disease Exacerbations

7 Jun 2023

Abstract excerpt

Abstract Rationale Acute exacerbations of chronic obstructive pulmonary disease (AE-COPDs) are associated with a significant disease burden. Blood immune phenotyping may improve our understanding of a COPD endotype at increased risk of exacerbations. Objective To determine the relationship between the transcriptome of circulating leukocytes and COPD exacerbations. Methods Blood RNA sequencing data (n = 3,618)...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 37286295
DOI: 10.1164/rccm.202301-0085oc

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