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Identification of pathogen genomic differences that impact human immune response and disease during <i>Cryptococcus neoformans</i> infection

2019-03-28

Abstract excerpt

Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen’s characteristics. To probe the influence of pathogen genotype on human immune response and disease, we examined Cryptococcus neoformans isolates collected during the Cryptococcal Optimal ART Timing (COAT) trial in Uganda. We measured human participants’ immunolog...

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Identifiers and source

Literature Corpus work
89a37598-450e-5dcd-9a36-ff541a114c73
DOI
10.1101/592212
Open publication

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Identification of pathogen genomic differences that impact human immune response and disease during <i>Cryptococcus neoformans</i> infectionDOI 10.1101/592212
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