Article
Genetic diversity and microevolution in clinical Cryptococcus isolates from Cameroon.
Medical mycology - 1 Dec 2023
Sephton-Clark Poppy, Temfack Elvis, Tenor Jennifer L, Toffaletti Dena L, Loyse Angela, Molloy Síle F, Perfect John R, Bicanic Tihana, Harrison Thomas S, Lortholary Olivier, Kouanfack Charles, Cuomo Christina A
Abstract excerpt
Cryptococcal meningitis is the second most common cause of death in people living with HIV/AIDS, yet we have a limited understanding of how cryptococcal isolates change over the course of infection. Cryptococcal infections are environmentally acquired, and the genetic diversity of these infecting isolates can also be geographically linked. Here, we employ whole genome sequences for 372 clinical Cryptococcus...
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