Article

Culture of Megakaryocytes from Human Peripheral Blood Mononuclear Cells

2015-01-01

Abstract excerpt

Megakaryocytes are the precursor cells of platelets and are bona fide resident cells in the bone marrow but extremely low in numbers (~1% of total nucleated cells). Upon terminal differentiation, megakaryocytes increase their size, become polyploid and develop a demarcation membrane system. Mature megakaryocytes form proplatelets, which are cytoplasmic extensions that protrude through the endothelial cell layer of...

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Literature Corpus work: 8935c7bb-7059-57f1-8d1a-e3d9ccd1273c
DOI: 10.21769/bioprotoc.1639

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