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The kinase inhibitor Palbociclib is a potent and specific RNA-binding molecule

2022-01-20

Abstract excerpt

The growing awareness of the role of RNA in human disease has motivated significant efforts to discover drug-like small molecules that target RNA. However, high throughput screening campaigns report very low hit rates and generally identify compounds with weak affinity, while most structures reported in Academic studies also lack the pharmacological properties of successful drugs. Even FDA-approved RNA-targeting d...

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Identifiers and source

Literature Corpus work
89359748-15fa-5a46-b9a9-bf821ffc8901
DOI
10.1101/2022.01.20.477126
Open publication

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The kinase inhibitor Palbociclib is a potent and specific RNA-binding moleculeDOI 10.1101/2022.01.20.477126
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