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Article

Loss of transcriptional heterogeneity in aged human muscle stem cells

2022-05-11

Abstract excerpt

<h4>ABSTRACT</h4> Age-related loss of muscle mass and function negatively impacts healthspan and lifespan. Satellite cells function as muscle stem cells in muscle maintenance and regeneration by self-renewal, activation, proliferation and differentiation. These processes are perturbed in aging at the stem cell population level, contributing to muscle loss. However, how representation of subpopulations within the...

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Literature Corpus work
89103d94-6a65-5c07-8120-c44d8c13969c
DOI
10.1101/2022.05.11.491465
Open publication

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Loss of transcriptional heterogeneity in aged human muscle stem cellsDOI 10.1101/2022.05.11.491465
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