Article

Unifying design principles of endocrine gland mass and its regulatory circuits

2023-07-03

Abstract excerpt

Hormones are regulatory molecules that impact physiological functions. Much is known about individual hormones, but general rules that connect the regulatory logic of different hormone systems are limited. In this study, we analyzed a range of human hormone systems using a mathematical approach to integrate knowledge on endocrine cells, target tissues and regulation, to uncover unifying principles and regulatory c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 88c84b0b-89bb-5d16-b7e9-7fd26d18a543
DOI: 10.1101/2023.07.03.547486

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unifying design principles of endocrine gland mass and its regulatory circuitsDOI 10.1101/2023.07.03.547486Read

Interference with Systemic Negative Feedback Regulation as a Potential Mechanism for Nonmonotonic Dose-Responses of Endocrine-Disrupting ChemicalsSemantic proximity Read

Mathematical modeling approaches of cellular endocrinology within the hypothalamo-pituitary-gonadal axisSemantic proximity Read

Integrated network systems and evolutionary developmental endocrinology.Semantic proximity Read

Integrating theoretical and empirical approaches for a robust understanding of endocrine flexibility.Semantic proximity Read

Human hormone seasonalitySemantic proximity Read

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptomeSemantic proximity Read

Pituitary multi-hormone cells in mammals and fish: history, origin, and rolesSemantic proximity Read

Revealing the large-scale network organization of growth hormone-secreting cellsSemantic proximity Read

Comparative endocrinology in the 21st centurySemantic proximity Read

Adaptive receptor expression and the emergence of disease as loss of signaling homeostasisSemantic proximity Read

The Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer.Semantic proximity Read

Bayesian metamodeling of complex biological systems across varying representationsSemantic proximity Read