Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revealing the large-scale network organization of growth hormone-secreting cells

4 Nov 2005

Abstract excerpt

Pituitary growth hormone (GH)-secreting cells regulate growth and metabolism in animals and humans. To secrete highly ordered GH pulses (up to 1,000-fold rise in hormone levels in vivo), the pituitary GH cell population needs to mount coordinated responses to GH secretagogues, yet GH cells display an apparently heterogeneous scattered distribution in 2D histological studies. To address this paradox, we analyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axon Guidance and Neuronal Signaling
Share to Growth Hormone and Insulin-like Growth Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16272219
DOI: 10.1073/pnas.0508202102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revealing the large-scale network organization of growth hormone-secreting cellsPMID 16272219Read ↗

Pituitary multi-hormone cells in mammals and fish: history, origin, and rolesSemantic proximity Read ↗

Spatial and functional mapping of the human pancreas reveals endocrine and exocrine cell states in health and metabolic diseaseSemantic proximity Read ↗

Integrating single-cell imaging and RNA sequencing datasets links differentiation and morphogenetic dynamics of human pancreatic endocrine progenitorsSemantic proximity Read ↗

Single cell transcriptomic analysis of the adult mouse pituitary reveals a novel multi-hormone cell cluster and physiologic demand-induced lineage plasticitySemantic proximity Read ↗

A combined transcriptional and dynamic roadmap of single human pancreatic endocrine progenitors reveals proliferative capacity and differentiation continuumSemantic proximity Read ↗

Unifying design principles of endocrine gland mass and its regulatory circuitsSemantic proximity Read ↗

Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.Semantic proximity Read ↗

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafishSemantic proximity Read ↗

Phenotypic characterization of multi-functional somatotropes, mammotropes and gonadotropes of the mouse anterior pituitary.Semantic proximity Read ↗

From Isles of Königsberg to Islets of Langerhans: Examining the Function of the Endocrine Pancreas Through Network ScienceSemantic proximity Read ↗

Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism.Semantic proximity Read ↗

Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.