Article
The Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer.
Hormones & cancer - 1 Jun 2016
Capper Cameron P, Rae James M, Auchus Richard J
Abstract excerpt
Breast and prostate cancers are malignancies in which steroid hormones drive cellular proliferation. Over the past century, this understanding has led to successful treatment strategies aimed to inhibit hormone-mediated tumor growth. Nonetheless, disease relapse and progression still pose significant clinical problems, with recurrent and metastatic tumors often exhibiting resistance to current drug therapies. The...
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