Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated network systems and evolutionary developmental endocrinology.

Medical hypotheses - 1 Jan 2010

Koshiyama Hiroyuki, Ogawa Yoshihiro, Tanaka Kiyoshi, Tanaka Issei

Abstract excerpt

Endocrine system has been considered to be a linear one, but the 'real world endocrine system' is a complex system, which is difficult to investigate using conventional strategies, such as single nucleotide polymorphism, genome-wide analysis, or gene targeting in animals. Here we propose a new strategy to comprehend the endocrine system as a complex network system. We introduced several novel concepts, such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coenzyme A
Share to Adenosine Triphosphate
Share to Developmental Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endocrine System

Share to Gene Targeting

Share to Models, Theoretical

Share to Systems Biology

Source

Identifiers

PMID: 19674847
DOI: 10.1016/j.mehy.2009.07.028

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated network systems and evolutionary developmental endocrinology.PMID 19674847Read ↗

Co-evolution analysis on endocrine research: a methodological approach.Semantic proximity Read ↗

A model system for identifying genes underlying complex traits.Semantic proximity Read ↗

Network medicine approaches to the genetics of complex diseases.Semantic proximity Read ↗

Systematic large-scale study of the inheritance mode of Mendelian disorders provides new insight into human diseasome.Semantic proximity Read ↗

Internetwork connectivity of molecular networks across species of lifeSemantic proximity Read ↗

Evolution, interactions, and biological networks.Semantic proximity Read ↗

Genetic Causation in Complex Regulatory Systems: An Integrative Dynamic Perspective.Semantic proximity Read ↗

Heterogeneity-mediated cellular adaptation and its trade-off: searching for the general principles of diseases.Semantic proximity Read ↗

Maneuvering in the complex path from genotype to phenotype.Semantic proximity Read ↗

Disease-aging network reveals significant roles of aging genes in connecting genetic diseases.Semantic proximity Read ↗

Network-based analysis of key regulatory genes implicated in Type 2 Diabetes Mellitus and Recurrent Miscarriages in Turner Syndrome.Semantic proximity Read ↗

NIDDM enigma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.