Article

Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice

2017-10-11

Abstract excerpt

Ancestral environmental exposures to non-mutagenic agents can exert effects in unexposed descendants. This transgenerational inheritance has significant implications for understanding disease etiology. The obesogen hypothesis proposes that exposure to obesogenic chemicals can lead to increased adiposity, in vivo . Here we show that exposure of F0 mice to the obesogen tributyltin (TBT) throughout pregnancy and lac...

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Literature Corpus work: 88a83e38-5135-5945-bb97-6173b226b1be
DOI: 10.1101/201384

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