Article

Paternal obesity and epigenetic inheritance of breast cancer: The role of systemic effects and transmission to the second generation

2020-06-06

Abstract excerpt

<h4>Background</h4> While genetics explains some familial breast cancer cases, we showed that environmentally-induced epigenetic inheritance of breast cancer can also occur in rodent models. We previously reported that paternal consumption of a high-fat diet and ensuing obesity increased breast cancer susceptibility in the offspring (F1). Nevertheless, it is still unclear whether paternal-induced programming of b...

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Literature Corpus work: 9905013a-8f7d-5d7a-9420-22463edfc875
DOI: 10.1101/2020.06.05.136234

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