Article

Assesses of Chronic Lymphocytic Leukemia Cases with Isoform p53 Protein using Elisa Method

2024-07-16

Abstract excerpt

<h4>Background: </h4> P53 gene mutation is a very common event in human neoplasia, and genetic mutations in the P53 gene in a single allele are responsible for a hereditary cancer susceptibility syndrome (Li Fraumeni). These variants encode distinct isoforms of the p53 protein, which may disrupt its transcriptional activity. These point mutant proteins are more stable than the normal protein and the mutant product...

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Literature Corpus work: 8880557f-a395-5cee-8600-7cabb1d13190
DOI: 10.20944/preprints202407.1260.v1

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