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Article

Frequency Of TP53 Gene Mutation In Patients With Chronic Lymphocytic Leukaemia.

Journal of Ayub Medical College, Abbottabad : JAMC - 1 Jan 2000

Qadir Hira, Nasir Nadia, Qadir Nida, Adil Salman Naseem, Tanzeem Hammad, Qadir Areesha

Abstract excerpt

BACKGROUND: Chronic lymphocytic leukaemia (CLL), an indolent but malignant lymphoproliferative disorder, is characterized by unregulated and uninhibited growth of mature monoclonal lymphocytes, with deletion of 17p containing TP53 gene being the most important prognostic factor. TP53 mutations, reported in 10% of CLL cases, seem to have a direct correlation to a more advanced stage and aggressive transformation...

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PMID: 33225656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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