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Importance of the Aspergillus fumigatus Mismatch Repair Protein Msh6 in Antifungal Resistance Development

12 Mar 2024

Abstract excerpt

One of the systems responsible for the recognition and repair of mistakes occurring during cell replication is the DNA mismatch repair (MMR) system. Two major protein complexes constitute the MMR pathway: MutS and MutL. Here, we investigated the possible relation of four A. fumigatus MMR genes (msh2, msh6, pms1, and mlh1) with the development of azole resistance related to the phenomenon of multi-drug resistance....

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PMID: 38535218
DOI: 10.3390/jof10030210

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