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Article

Molecular dissection of the human multidrug resistance P-glycoprotein

1999-03-01

Abstract excerpt

The human multidrug resistance P-glycoprotein is an ATP-dependent drug pump that extrudes a broad range of cytotoxic agents from the cell. Its physiological role may be to protect the body from endogenous and exogenous cytotoxic agents. The protein has clinical importance because it contributes to the phenomenon of multidrug resistance during chemotherapy. In this review, we discuss some of the results obtained by...

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Literature Corpus work
884d3ce6-0ce2-5df5-8102-571975f0cc84
DOI
10.1139/o99-014
Open publication

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Molecular dissection of the human multidrug resistance P-glycoproteinDOI 10.1139/o99-014
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