Article
Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast.
The Journal of biological chemistry - 29 Apr 1994
Decottignies A, Kolaczkowski M, Balzi E, Goffeau A
Abstract excerpt
A 160-kDa plasma membrane protein of the yeast Saccharomyces cerevisiae was overexpressed by mutating the PDR1 or the PDR3 transcription factor gene. The protein is the membrane-bound ATP binding cassette transporter PDR5 (Balzi, E., Wang, M., Leterme, S., Van Dyck, L., and Goffeau, A. (1994) J....
Topics
- ATP-Binding Cassette Transporters
- Adenosine Triphosphatases
- Carrier Proteins
- Cell Membrane
- Drug Resistance
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- Fungal Proteins
- Hydrolysis
- Membrane Proteins
- Mutation
- Pyrophosphatases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Solubility