Article

Phase-space distance between stationary states modulates phenotypic plasticity in breast cancer

2026-03-10

Abstract excerpt

Phenotypic plasticity in breast cancer involves stochastic transitions between gene-expression states associated with clinically distinct subtypes, such as HER2+ and triple-negative breast cancer (TNBC). In non-conservative gene regulatory networks, however, the dynamical features controlling transition probabilities and timescales cannot be consistently reduced to potential-barrier depth, since potential function...

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Literature Corpus work: 882f3513-98b6-53cd-97f5-70729b4a6649
DOI: 10.64898/2026.03.06.710190

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