Article

BiomiX-Driven Multi-Omics Integration of PRECISESADS Data Reveals Lysophosphatidic Acid and Metabolic Pathway Signatures in B Cells and Immune Macroenvironment in Sjögren’s Disease

2025-12-02

Abstract excerpt

<h4>Objective</h4> Sjögren’s disease (SjD) is a systemic autoimmune disorder characterized by lymphocytic infiltration of exocrine glands, resulting in xerostomia, keratoconjunctivitis sicca, fatigue, arthralgia, and systemic organ involvement. This study aimed to characterize the metabolic and immune dysregulation of SjD using a multi-omics approach, focusing on the metabolic environment and B-cell transcriptomi...

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Literature Corpus work: 882c1056-c0ab-56a2-b68f-dcfef835d236
DOI: 10.64898/2025.11.30.690253

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