Article

Machine Learning Approach to Single Cell Transcriptomic Analysis of Sjogren’s Disease Reveals Altered Activation States of B and T Lymphocytes

2024-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Sjogren’s Disease (SjD) is an autoimmune disorder characterized by salivary and lacrimal gland dysfunction and immune cell infiltration leading to gland inflammation and destruction. Although SjD is a common disease, its pathogenesis is not fully understood. In this study, we conducted a single-cell transcriptome analysis of peripheral blood mononuclear cells (PBMC) from patients with SjD and sy...

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Literature Corpus work: 23b22438-568a-559b-aa8c-b2cbd9e0db15
DOI: 10.1101/2024.10.28.620603

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