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Article

Genetic, Transcriptomic, and Epigenomic Insights into Sjögren's Disease: An Integrative Network Investigation and Immune Diseases Comparison.

International journal of molecular sciences - 13 May 2025

Enduru Nitesh, Manuel Astrid M, Zhao Zhongming

Abstract excerpt

Sjögren's disease (SjD) is a systemic autoimmune disorder primarily causing dry eyes and mouth. It frequently overlaps with other autoimmune diseases (AIDs), including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). However, the genetic basis of SjD remains underexplored, limiting our understanding of its connections to other immune-mediated conditions. In this study, we aimed to identify gene...

Topics

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DNA Methylation
Epigenesis, Genetic
Epigenomics
Gene Expression Profiling
Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Sjogren's Syndrome

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Identifiers

PMID: 40429780
DOI: 10.3390/ijms26104637
PMCID: PMC12111751

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