Article

Integrated Multi-Omics Profiling Reveals Neutrophil Extracellular Traps Promote Aortic Dissection

2023-12-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background and Aims</bold>: Adverse aortic remodeling increases the risk of aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) and affects the overall prognosis of aortic dissection (AD). It is imperative to delve into the exploration of prognostic indicators to streamline the identification of individuals at elevated risk for postoperative AAEs,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 881d7b90-900c-56f0-ae4d-9f101edd97b7
DOI: 10.21203/rs.3.rs-3707669/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrated Multi-Omics Profiling Reveals Neutrophil Extracellular Traps Promote Aortic DissectionDOI 10.21203/rs.3.rs-3707669/v1Read

Identification of key biomarkers and immune infiltration in the thoracic acute aortic dissection by bioinformatics analysisSemantic proximity Read

Identification and Experimental Validation of NETosis-Mediated Abdominal Aortic Aneurysm Gene Signature Using Multi-omics, Machine Learning, and Mendelian RandomizationSemantic proximity Read

Common molecular mechanism and immune infiltration patterns of thoracic and abdominal aortic aneurysmsSemantic proximity Read

Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2Semantic proximity Read

Integrative mediation and multi-omics analysis to decode Aortic dissection’s genetic causal phenotype and potential therapeutic targetsSemantic proximity Read

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Protective Effects of Fenofibrate in Acute Type A Aortic DissectionSemantic proximity Read

Identification of Serum Biomarkers and Therapeutic Targets for Aortic Diseases in Obesity through Multi-Omics AnalysisSemantic proximity Read

Single-Cell Transcriptomic Analysis Reveals Differential Cell Subpopulations and Distinct Phenotype Transition in Normal and Dissected Ascending AortaSemantic proximity Read

Epigenetic Programming of Macrophage Phenotypes by STING–IRF3 Drives Inflammation in Ascending Thoracic Aortic DissectionSemantic proximity Read

Elucidating thoracic aortic dissection pathogenesis: The interplay of m1A-related gene expressions and miR-16-5p/YTHDC1 Axis in NLRP3-dependent pyroptosisSemantic proximity Read

CTHRC1 is a new therapeutic target and serum diagnostic biomarker for aortic dissectionSemantic proximity Read

Multi-omics in thoracic aortic aneurysm: the complex road to the simplificationSemantic proximity Read