Tissue-wide Metabolomics Reveals Wide Impact of Gut Microbiota on Mice Metabolite Composition

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe essential role of gut microbiota in health and disease is well recognized, but the biochemical details that underlie the beneficial impact remain largely undefined. To maintain its stability, microbiota participates in an interactive host-microbiota metabolic signaling, impacting the metabolic phenotypes of the host. Dysbiosis of gut bacteria results in the alteration of c...

Topics

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• Bile Acids and Salts
• Diet and metabolism studies
• Diet, Metabolism, and Disease
• Gastrointestinal Tract
• Gut microbiota and health
• Kidney
• Metabolomics and Mass Spectrometry Studies
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

8819c530-f1bf-5de8-88ea-e83d368b182e

DOI

10.21203/rs.3.rs-930647/v1