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A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model

22 May 2007

Abstract excerpt

Symbiotic gut microorganisms (microbiome) interact closely with the mammalian host's metabolism and are important determinants of human health. Here, we decipher the complex metabolic effects of microbial manipulation, by comparing germfree mice colonized by a human baby flora (HBF) or a normal flora to conventional mice. We perform parallel microbiological profiling, metabolic profiling by (1)H nuclear magnetic...

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PMID: 17515922
DOI: 10.1038/msb4100153

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