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Gut bacteria–host metabolic interplay during conventionalisation of the mouse germfree colon

22 Nov 2012

Abstract excerpt

The interplay between dietary nutrients, gut microbiota and mammalian host tissues of the gastrointestinal tract is recognised as highly relevant for host health. Combined transcriptome, metabonome and microbial profiling tools were employed to analyse the dynamic responses of germfree mouse colonic mucosa to colonisation by normal mouse microbiota (conventionalisation) at different time-points during 16 days....

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PMID: 23178667
DOI: 10.1038/ismej.2012.142

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