Back to search

Article

The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence

2023-03-21

Abstract excerpt

Transmembrane protein 106B (TMEM106B), a protein that is localized to the lysosome, is genetically linked to many neurodegenerative diseases and forms fibrils in diseased brains. The reproducibility of TMEM106B research would be enhanced if the community had access to well-characterized anti-TMEM106B antibodies. In this study, we characterized six commercially available TMEM106B antibodies for their performance in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
880dd34f-53a3-55b7-8588-29c97f81cbf1
DOI
10.12688/f1000research.131333.1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescenceDOI 10.12688/f1000research.131333.1
The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescenceSemantic proximity
The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for Optineurin (UniProt ID: Q96CV9) for use in western blot, immunoprecipitation, and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for GCase (UniProt ID: P04062) for use in western blot, immunoprecipitation, and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescenceSemantic proximity
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.Semantic proximity
The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescenceSemantic proximity
A guide to selecting high-performing antibodies for ASM (UniProt ID: P17405) for use in western blot and immunoprecipitationSemantic proximity
A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescenceSemantic proximity
Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal healthSemantic proximity
Select a neighboring publication to make it the new centre.