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Pyroptosis burden is associated with anti-TNF treatment outcome in inflammatory bowel disease: new insights from bioinformatics analysis

22 Sept 2023

Abstract excerpt

Biological agents known as anti-tumor necrosis factor (TNF) drugs are frequently utilized in the treatment of inflammatory bowel disease (IBD). In this study, we analyzed the shared processes of pyroptosis in Ulcerative colitis (UC) and Crohn's disease (CD), as well as explored the correlation between the burden of pyroptosis and the results of anti-TNF treatment based on bioinformatics analyses. We identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37740137
DOI: 10.1038/s41598-023-43091-0

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