Article

Comparison of Different Approaches to Single Cell RNA Sequencing of Cancer Associated Fibroblasts

2024-05-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a poor prognosis. PDAC has a high propensity for metastasis, particularly to the lungs and liver. Cancer associated fibroblasts (CAFs) represent a major stromal component of PDAC with both tumor-promoting and restraining properties. Of note, CAFs play a significant role in the creation of an immunosu...

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Literature Corpus work: 87a7ccde-a3f4-5da7-b2c9-488cfffb7a6f
DOI: 10.1101/2024.04.29.591011

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