Article
Profiling and leveraging relatedness in a precision medicine cohort of 92,455 exomes
2017-10-03
Abstract excerpt
Large-scale human genetics studies are ascertaining increasing proportions of populations as they continue growing in both number and scale. As a result, the amount of cryptic relatedness within these study cohorts is growing rapidly and has significant implications on downstream analyses. We demonstrate this growth empirically among the first 92,455 exomes from the DiscovEHR cohort and, via a custom simulation fr...
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Identifiers and source
- Literature Corpus work
- 878eccf8-b5a8-5d07-879f-a1419c8ef07e
- DOI
- 10.1101/197889