Article

Bidirectional Association and Genetic Background of Anxiety Disorders and General Medical Conditions

2025-10-13

Abstract excerpt

<h4>Importance</h4> Anxiety disorders are often comorbid with general medical conditions, but the extent and directionality of these associations and shared genetic risk factors are not well understood. <h4>Objective</h4> To investigate the potential associations and the directionality between anxiety disorders and general medical conditions, and to explore the underlying shared genetic risk. <h4>Design</h4> We...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 877d961a-1824-50aa-aaad-fc5f2849dc49
DOI: 10.1101/2025.10.10.25337730

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bidirectional Association and Genetic Background of Anxiety Disorders and General Medical ConditionsDOI 10.1101/2025.10.10.25337730Read

Disease clusters subsequent to anxiety and stress-related disorders and their genetic determinants.Semantic proximity Read

Comorbidity alters the genetic relationship between anxiety disorders and major depressionSemantic proximity Read

The contribution of genetic risk to the comorbidity of depression and anxiety: a multi-site electronic health records studySemantic proximity Read

Causal relationships between psychological disorders and functional gastrointestinal disorders: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.Semantic proximity Read

Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry.Semantic proximity Read

The structure of genetic and environmental risk factors for anxiety disorders in men and women.Semantic proximity Read

Causal relationships between psychological disorders and functional gastrointestinal disorders: a bidirectional two-sample Mendelian randomization studySemantic proximity Read

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signalingSemantic proximity Read

Phenome-wide investigation of bidirectional causal relationships between major depressive disorder and common human diseases.Semantic proximity Read

Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis.Semantic proximity Read

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.Semantic proximity Read