Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in diminished ovarian reserve and premature ovarian insufficiency: implications for assisted reproductive outcomes.

Journal of assisted reproduction and genetics - 1 Nov 2025

Xu Qianhua, Ding Haitian, Liu Yingchun, Han Dan, Xia Xun, Li Yuqian, Sha Xuan, Li Guotong, Ni Xiaoqing, Li Kuokuo, Hua Rong, He Xiaojin, Wu Huan, Cao Yunxia, Xu Yuping

Abstract excerpt

OBJECTIVE: To investigate the genetic factors underlying diminished ovarian reserve (DOR) and premature ovarian insufficiency (POI) in 55 infertile women of reproductive age in China and to evaluate the outcomes of assisted reproductive technology (ART) treatment in cases of genetically associated DOR/POI. METHODS: Whole-exome sequencing was performed to identify pathogenic gene variants associated with DOR and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exome Sequencing
Share to NBN gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Heterozygote

Share to Pedigree

Share to Primary Ovarian Insufficiency

Share to Prognosis

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 40936058
DOI: 10.1007/s10815-025-03663-7
PMCID: PMC12640392

Genes

BNC1
EIF2B5
HFM1
MCM9
MSH4
MSH5
NBN
NOBOX
REC114
TBPL2
TWNK
UMODL1
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in diminished ovarian reserve and premature ovarian insufficiency: implications for assisted reproductive outcomes.PMID 40936058Read ↗

Landscape of pathogenic mutations in premature ovarian insufficiency.Semantic proximity Read ↗

Genetic Landscape of a Cohort of 120 Patients with Diminished Ovarian Reserve: Correlation with InfertilitySemantic proximity Read ↗

Exome Sequencing of a Primary Ovarian Insufficiency Cohort Reveals Common Molecular Etiologies for a Spectrum of DiseaseSemantic proximity Read ↗

Genetics of ovarian insufficiency and defects of folliculogenesis.Semantic proximity Read ↗

An exome-wide exploration of cases of primary ovarian insufficiency uncovers novel sequence variants and candidate genes.Semantic proximity Read ↗

Genetics of Primary Ovarian Insufficiency in the Next-Generation Sequencing EraSemantic proximity Read ↗

Whole-exome sequencing in patients with premature ovarian insufficiency: early detection and early interventionSemantic proximity Read ↗

Genetic architecture and phenotypic diversity of oocyte and early embryo competence defects in female infertility.Semantic proximity Read ↗

Targeted Next-Generation Sequencing Indicates a Frequent Oligogenic Involvement in Primary Ovarian Insufficiency Onset.Semantic proximity Read ↗

Selected Genetic Factors Associated with Primary Ovarian Insufficiency.Semantic proximity Read ↗

Genetic insights into the complexity of premature ovarian insufficiency.Semantic proximity Read ↗

Next-generation sequencing of 500 POI patients identified novel responsible monogenic and oligogenic variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.