Article

Multimodal profiling of human sensory neurons links electrical properties to transcriptional identity

2025-03-26

Abstract excerpt

Despite major advances in pain science, the approval of novel therapeutics has been slow. A major cause for the lack of new analgesics may be fundamental biological differences between humans and model organisms used in preclinical research. Large-scale transcriptional profiling efforts on human dorsal root ganglia (hDRG) have now identified at least 22 distinct neuronal subtypes; however, a significant knowledge...

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Literature Corpus work: 87679a60-7989-5b3c-9791-20cce4e93615
DOI: 10.1101/2025.03.25.645367

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