Article

eIF2α mediated integrated stress response connects multiple intracellular signaling to reprogram vascular smooth muscle cell fate in carotid plaques

2022-09-09

Abstract excerpt

<h4>Background: </h4> As a well-recognized pathological basis of ischemic stroke, the molecular mechanisms of atherosclerotic carotid artery stenosis remain unclear. Vascular smooth muscle cells (VSMCs) play a fundamental role in the initiation and progression of atherosclerosis. The involvement of organelle dynamics has been uncovered in the development of atherosclerosis in the past decade. However, systematic s...

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Literature Corpus work: 8717607c-258f-519b-81dd-7b1a498d6aa9
DOI: 10.21203/rs.3.rs-2022646/v1

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