Article

<i>RFC1</i> regulates the expansion of neural progenitors in the developing zebrafish cerebellum

2024-06-28

Abstract excerpt

<h4>Summary</h4> DNA replication and repair are basic yet essential molecular processes for all cells. RFC1 encodes the largest subunit of the Replication Factor C (RFC), which is a clamp-loader during DNA replication and repair. Intronic repeat expansion in RFC1 has recently been associated with so-called RFC1 -related disorders, which mainly encompass late-onset cerebellar ataxias. However, the mechanisms th...

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Literature Corpus work: 86fa9089-2e53-59d6-b775-0f5052c08f49
DOI: 10.1101/2024.06.28.601164

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