Article

Navigome: Navigating the Human Phenome

2018-10-22

Abstract excerpt

We now have access to a sufficient number of genome-wide association studies (GWAS) to cluster phenotypes into genetic-informed categories and to navigate the “phenome” space of human traits. Using a collection of 465 GWAS, we generated genetic correlations, pathways, gene-wise and tissue-wise associations using MAGMA and S-PrediXcan for 465 human traits. Testing 7267 biological pathways, we found that only 898 we...

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Literature Corpus work: 86ed8d91-1b46-5479-8fd0-8449316d7591
DOI: 10.1101/449207

Open publication

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