NETMAGE: A human disease phenotype map generator for the network-based visualization of phenome-wide association study results.

Abstract excerpt

BACKGROUND: Disease complications, the onset of secondary phenotypes given a primary condition, can exacerbate the long-term severity of outcomes. However, the exact cause of many of these cross-phenotype associations is still unknown. One potential reason is shared genetic etiology-common genetic drivers may lead to the onset of multiple phenotypes. Disease-disease networks (DDNs), where nodes represent diseases...

Topics

Join the communities discussing this publication.

• Genome-Wide Association Study
• Phenotype
• Polymorphism, Single Nucleotide