Article
Deep phenotyping of health-disease continuum in the Human Phenotype Project.
Nature medicine - 1 Sept 2025
Reicher Lee, Shilo Smadar, Godneva Anastasia, Lutsker Guy, Zahavi Liron, Shoer Saar, Krongauz David, Rein Michal, Kohn Sarah, Segev Tomer, Schlesinger Yishay, Barak Daniel, Levine Zachary, Keshet Ayya, Shaulitch Rotem, Lotan-Pompan Maya, Elkan Matan, Talmor-Barkan Yeela, Aviv Yaron, Dadiani Maya, Tsodyks Yonatan, Gal-Yam Einav Nili, Leibovitzh Haim, Werner Lael, Tzadok Roie, Maharshak Nitsan, Koga Shin, Glick-Gorman Yulia, Stossel Chani, Raitses-Gurevich Maria, Golan Talia, Dhir Raja, Reisner Yotam, Weinberger Adina, Rossman Hagai, Song Le, Xing Eric P, Segal Eran
Abstract excerpt
The Human Phenotype Project (HPP) is a large-scale deep-phenotype prospective cohort. To date, approximately 28,000 participants have enrolled, with more than 13,000 completing their initial visit. The project is aimed at identifying novel molecular signatures with diagnostic, prognostic and therapeutic value, and at developing artificial intelligence (AI)-based predictive models for disease onset and...
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