Article

Gut-derived metabolite 3-methylxanthine enhances cisplatin-induced apoptosis via dopamine receptor D1 in a mouse model of ovarian cancer

2023-10-30

Abstract excerpt

<title>Abstract</title> <p>Background Platinum-based chemotherapy failure represents a significant challenge in the management of ovarian cancer (OC) and contributes to disease recurrence and poor prognosis. Recent studies have shed light on the involvement of the gut microbiota in modulating anticancer treatments. However, the precise underlying mechanisms by which the gut microbiota regulates the response to p...

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Literature Corpus work: 86d56b8b-172e-510e-8755-35946189722b
DOI: 10.21203/rs.3.rs-3501298/v1

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