Article
Ginseng Protects Against Cisplatin-Induced Liver Failure by Regulating Drug-Metabolizing Enzymes
2026-04-27
Abstract excerpt
<h4>Background: </h4> Cisplatin is a widely used chemotherapeutic agent; however, its clinical application is limited by severe adverse effects, including hepatotoxicity. Natural antioxidants may offer protective strategies against such toxicity. Methods Male rats were treated intraperitoneally with cisplatin (4 mg/kg body weight/week) for three months to induce hepatotoxicity. Ginseng was administered orally at a...
Topics
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- Acute Lymphoblastic Leukemia research
- Autophagy in Disease and Therapy
- Chemotherapy-induced cardiotoxicity and mitigation
- Chemotherapy-induced organ toxicity mitigation
- Drug-Induced Hepatotoxicity and Protection
- Drug Transport and Resistance Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Sirtuins and Resveratrol in Medicine
Identifiers and source
- Literature Corpus work
- 0edc5272-ff83-5682-8b2f-1df5a610dc84
- DOI
- 10.12688/f1000research.174662.1
