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<i>ESR1</i> , <i>WT1</i> , <i>WNT4, ATM</i> and <i>TERT</i> loci are major contributors to uterine leiomyoma predisposition

2018-03-29

Abstract excerpt

<h4>ABSTRACT</h4> Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 5,417 UL cases and 331,791 controls was performed, followed by replication of the genomic risk in two cohorts. Effects of the identified risk alleles were evaluated in view of molecular and clinical features. Five loci displayed a genome-wide significant association; the previ...

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Literature Corpus work
86c4def9-517b-5d36-b381-7bec26ea2146
DOI
10.1101/291237
Open publication

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