Article
Development and optimization of a rat Purkinje neuron culture to study paraneoplastic cerebellar degeneration
2022-04-06
Abstract excerpt
<title>Abstract</title> <p><bold>Background:</bold> Elucidation of the mechanisms involved in neurodegenerative disease has been hampered by the lack of robust cellular models that replicate <italic>in vivo</italic> features. <bold>Methods:</bold> We developed a refined protocol for generation of age-dependent, well-developed, and synaptically active rat Purkinje neurons in a multilayer cell network culture that...
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Identifiers and source
- Literature Corpus work
- 86bbc259-44d3-52a1-8c46-cb92fd665652
- DOI
- 10.21203/rs.3.rs-1505572/v1