Article

Multiplexed nanopore sequencing of HLA-B locus in Māori and Polynesian samples

2017-07-27

Abstract excerpt

The human leukocyte antigen (HLA) system is a gene family that encodes the human major histocompatibility complex (MHC). HLA-B is the most polymorphic gene in the MHC class I region, comprised of 4,765 HLA-B alleles (IPD-IMGT/HLA Database Release 3.28). Many HLA-B alleles have been associated with adverse drug reactions and disease risks, and we are interested in developing efficient methods for analysis of HLA al...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8685703c-86e2-5366-9c9e-55c6d8c68fc2
DOI: 10.1101/169078

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiplexed nanopore sequencing of HLA-B locus in Māori and Polynesian samplesDOI 10.1101/169078Read

Ultrarapid and high-resolution HLA class I typing using transposase-based nanopore sequencing applied in pharmacogenetic testingSemantic proximity Read

HLA/MHC and KIR characterization in humans and non-human primates using Oxford Nanopore Technologies and Pacific Biosciences sequencing platforms.Semantic proximity Read

Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA GenesSemantic proximity Read

Rapid, highly accurate and cost-effective open-source simultaneous complete HLA typing and phasing of class I and II alleles using nanopore sequencing.Semantic proximity Read

Long-Read Nanopore Sequencing Validated for Human Leukocyte Antigen Class I Typing in Routine Diagnostics.Semantic proximity Read

High-resolution HLA typing by long reads from the R10.3 Oxford nanopore flow cells.Semantic proximity Read

Long read nanopore sequencing for detection of HLA and CYP2D6 variants and haplotypesSemantic proximity Read

Single locus HLA sequencing with the nanopore technology for HLA disease association diagnosis.Semantic proximity Read

Long read nanopore sequencing for detection of HLA and CYP2D6 variants and haplotypesSemantic proximity Read

Accurate typing of class I human leukocyte antigen by Oxford nanopore sequencingSemantic proximity Read

Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing.Semantic proximity Read

A Simplified, Scalable Solution for Simultaneous Genotyping of Human Leukocyte Antigen Classical Class I and Human Platelet Antigen Genes Utilising Oxford Nanopore Technologies Long-Read Sequencing.Semantic proximity Read