Article

Concordance of whole-genome amplified embryonic DNA with the subsequently born child

2024-01-15

Abstract excerpt

Before implantation subsequent to in vitro fertilization (IVF), the current options for Preimplantation Genetic Testing (PGT) are PGT for Aneuploidy (PGT-A) and, if clinically indicated, PGT for monogenic conditions (PGT-M). A more comprehensive approach involves PGT whole genome sequencing (PGT-WGS). PGT-WGS incorporates PGT-A, screens for hundreds of monogenic conditions, and can evaluate polygenic risk. Here we...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 866d56b3-540a-5e52-9ac6-201aeecfd679
DOI: 10.1101/2024.01.12.24301086

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Concordance of whole-genome amplified embryonic DNA with the subsequently born childDOI 10.1101/2024.01.12.24301086Read

Genome-Wide Disease Screening of Early Human Embryos at Base-Pair ResolutionSemantic proximity Read

First clinical validation of whole genome screening on standard trophectoderm biopsies of preimplantation embryosSemantic proximity Read

The first clinical validation of whole-genome screening on standard trophectoderm biopsies of preimplantation embryosSemantic proximity Read

Genome-Wide Disease Screening in Early Human Embryos with Primary Template-Directed AmplificationSemantic proximity Read

Genome sequencing of human in vitro fertilisation embryos for pathogenic variation screeningSemantic proximity Read

Identifying risk variants for embryo aneuploidy using ultra-low coverage whole-genome sequencing from preimplantation genetic testingSemantic proximity Read

Multi-centre evaluation of a comprehensive preimplantation genetic test through haplotyping-by-sequencingSemantic proximity Read

The concordance rates of an initial trophectoderm biopsy with the rest of the embryo using PGTseq, a targeted next-generation sequencing platform for preimplantation genetic testing-aneuploidySemantic proximity Read

Comprehensive preimplantation genetic testing by massively parallel sequencingSemantic proximity Read

Whole-genome risk prediction of common diseases in human preimplantation embryosSemantic proximity Read

Concurrent Preimplantation Genetic Testing and Competence Assessment of Human Embryos by Transcriptome Sequencing.Semantic proximity Read

PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease riskSemantic proximity Read